Has an AFL game ever ended 104-49?
Exactly once. On September 11, 1926, Geelong beat Fitzroy 104-49, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 104-49 in league history.
That makes 104-49 the 3836th most common final score out of 6,607 that have ever occurred in AFL. One point away, 105-49 has happened never and 104-50 has happened 2 times.