Has an AFL game ever ended 105-43?
Exactly once. On June 7, 1947, Melbourne beat St Kilda 105-43, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 105-43 in league history.
That makes 105-43 the 3884th most common final score out of 6,649 that have ever occurred in AFL. One point away, 106-43 has happened 1 times and 105-44 has happened never.