Has an AFL game ever ended 106-45?
Exactly once. On August 21, 1999, Carlton beat St Kilda 106-45, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 106-45 in league history.
That makes 106-45 the 3884th most common final score out of 6,649 that have ever occurred in AFL. One point away, 107-45 has happened 5 times and 106-46 has happened never.