Has an AFL game ever ended 108-48?
Exactly once. On October 6, 1934, Sydney beat Geelong 108-48, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 108-48 in league history.
That makes 108-48 the 3836th most common final score out of 6,607 that have ever occurred in AFL. One point away, 109-48 has happened never and 108-49 has happened 2 times.