Has an AFL game ever ended 109-43?
Exactly once. On April 26, 1975, Footscray beat Richmond 109-43, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 109-43 in league history.
That makes 109-43 the 3884th most common final score out of 6,649 that have ever occurred in AFL. One point away, 110-43 has happened 2 times and 109-44 has happened 2 times.