Has an AFL game ever ended 109-46?
Exactly once. On August 23, 1924, Fitzroy beat St Kilda 109-46, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 109-46 in league history.
That makes 109-46 the 3836th most common final score out of 6,607 that have ever occurred in AFL. One point away, 110-46 has happened 3 times and 109-47 has happened 3 times.