Has an AFL game ever ended 109-54?
Exactly once. On April 25, 1970, St Kilda beat Richmond 109-54, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 109-54 in league history.
That makes 109-54 the 3884th most common final score out of 6,649 that have ever occurred in AFL. One point away, 110-54 has happened 5 times and 109-55 has happened 4 times.