Has an AFL game ever ended 110-40?
Exactly once. On August 27, 1966, Geelong beat Carlton 110-40, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 110-40 in league history.
That makes 110-40 the 3836th most common final score out of 6,607 that have ever occurred in AFL. One point away, 111-40 has happened never and 110-41 has happened 1 times.