Has an AFL game ever ended 110-63?
Yes. AFL has seen a final score of 110-63 6 times. It first happened on April 30, 1927, when Essendon beat Footscray, and most recently on July 28, 2013, when Sydney beat Richmond.
That makes 110-63 the 342nd most common final score out of 6,607 that have ever occurred in AFL. One point away, 111-63 has happened 4 times and 110-64 has happened 3 times. At one point the score disappeared for 50 years, between 1927 and 1977.