Has an AFL game ever ended 115-48?
Exactly once. On April 15, 2018, Hawthorn beat Melbourne 115-48, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 115-48 in league history.
That makes 115-48 the 3836th most common final score out of 6,607 that have ever occurred in AFL. One point away, 116-48 has happened 1 times and 115-49 has happened 3 times.