Has an AFL game ever ended 120-22?
Exactly once. On August 26, 1899, Essendon beat St Kilda 120-22, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 120-22 in league history.
That makes 120-22 the 3836th most common final score out of 6,607 that have ever occurred in AFL. One point away, 121-22 has happened never and 120-23 has happened never.