Has an AFL game ever ended 122-66?
Exactly once. On July 17, 1948, Essendon beat Hawthorn 122-66, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 122-66 in league history.
That makes 122-66 the 3836th most common final score out of 6,607 that have ever occurred in AFL. One point away, 123-66 has happened never and 122-67 has happened 3 times.