Has an AFL game ever ended 122-81?
It has. 122-81 has been a AFL final 6 times in 17,051 games. The first was Richmond beat Melbourne on May 5, 1934; the latest was Richmond beat St Kilda on August 27, 2017.
That makes 122-81 the 374th most common final score out of 6,649 that have ever occurred in AFL. One point away, 123-81 has happened 2 times and 122-82 has happened 1 times. At one point the score disappeared for 32 years, between 1941 and 1973.