Has an AFL game ever ended 125-52?
Yes. AFL has seen a final score of 125-52 4 times. It first happened on September 24, 1949, when Essendon beat Carlton, and most recently on August 8, 2004, when Port Adelaide beat Melbourne.
That makes 125-52 the 947th most common final score out of 6,607 that have ever occurred in AFL. One point away, 126-52 has happened never and 125-53 has happened 1 times. Nearly all of its occurrences fall between 1980 and 2009. At one point the score disappeared for 34 years, between 1949 and 1983.