Has an AFL game ever ended 125-72?
Yes. AFL has seen a final score of 125-72 3 times. It first happened on April 26, 1948, when Collingwood beat Sydney, and most recently on July 31, 2010, when Geelong beat Sydney.
That makes 125-72 the 1599th most common final score out of 6,649 that have ever occurred in AFL. One point away, 126-72 has happened 4 times and 125-73 has happened 4 times. At one point the score disappeared for 59 years, between 1951 and 2010.