Has an AFL game ever ended 143-68?
Exactly once. On April 3, 2021, Essendon beat St Kilda 143-68, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 143-68 in league history.
That makes 143-68 the 3836th most common final score out of 6,607 that have ever occurred in AFL. One point away, 144-68 has happened never and 143-69 has happened never.