Has an AFL game ever ended 150-81?
Exactly once. On August 26, 2012, Adelaide beat Melbourne 150-81, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 150-81 in league history.
That makes 150-81 the 3836th most common final score out of 6,607 that have ever occurred in AFL. One point away, 151-81 has happened never and 150-82 has happened 1 times.