Has an AFL game ever ended 154-121?
Exactly once. On September 1, 1979, Carlton beat Sydney 154-121, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 154-121 in league history.
That makes 154-121 the 3836th most common final score out of 6,607 that have ever occurred in AFL. One point away, 155-121 has happened never and 154-122 has happened never.