Has an AFL game ever ended 160-45?
Exactly once. On May 14, 1932, Geelong beat St Kilda 160-45, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 160-45 in league history.
That makes 160-45 the 3836th most common final score out of 6,607 that have ever occurred in AFL. One point away, 161-45 has happened never and 160-46 has happened never.