Has an AFL game ever ended 162-52?
Exactly once. On July 5, 2015, St Kilda beat Essendon 162-52, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 162-52 in league history.
That makes 162-52 the 3836th most common final score out of 6,607 that have ever occurred in AFL. One point away, 163-52 has happened never and 162-53 has happened never.