Has an AFL game ever ended 166-80?
Exactly once. On April 24, 1988, Carlton beat Sydney 166-80, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 166-80 in league history.
That makes 166-80 the 3836th most common final score out of 6,607 that have ever occurred in AFL. One point away, 167-80 has happened never and 166-81 has happened never.