Has an AFL game ever ended 188-50?
Exactly once. On June 2, 2006, Adelaide beat Essendon 188-50, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 188-50 in league history.
That makes 188-50 the 3836th most common final score out of 6,607 that have ever occurred in AFL. One point away, 189-50 has happened never and 188-51 has happened never.