Has an AFL game ever ended 38-10?
Exactly once. On June 23, 1900, Sydney beat Essendon 38-10, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 38-10 in league history.
That makes 38-10 the 3836th most common final score out of 6,607 that have ever occurred in AFL. One point away, 39-10 has happened never and 38-11 has happened never.