Has an AFL game ever ended 41-25?
Exactly once. On May 25, 1901, Fitzroy beat Sydney 41-25, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 41-25 in league history.
That makes 41-25 the 3836th most common final score out of 6,607 that have ever occurred in AFL. One point away, 42-25 has happened 1 times and 41-26 has happened never.