Has an AFL game ever ended 49-11?
Exactly once. On August 10, 1957, Melbourne beat St Kilda 49-11, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 49-11 in league history.
That makes 49-11 the 3836th most common final score out of 6,607 that have ever occurred in AFL. One point away, 50-11 has happened never and 49-12 has happened never.