Has an AFL game ever ended 50-46?
Exactly once. On August 30, 1902, Sydney beat Fitzroy 50-46, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 50-46 in league history.
That makes 50-46 the 3884th most common final score out of 6,649 that have ever occurred in AFL. One point away, 51-46 has happened 6 times and 50-47 has happened 5 times.