Has an AFL game ever ended 52-46?
Yes. AFL has seen a final score of 52-46 2 times. It first happened on August 24, 1912, when Carlton beat Sydney, and most recently on July 4, 1970, when St Kilda beat Footscray.
That makes 52-46 the 2421st most common final score out of 6,607 that have ever occurred in AFL. One point away, 53-46 has happened 2 times and 52-47 has happened 3 times. At one point the score disappeared for 58 years, between 1912 and 1970.