Has an AFL game ever ended 59-16?
Exactly once. On June 25, 1898, Essendon beat Fitzroy 59-16, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 59-16 in league history.
That makes 59-16 the 3836th most common final score out of 6,607 that have ever occurred in AFL. One point away, 60-16 has happened never and 59-17 has happened never.