Has an AFL game ever ended 60-25?
Exactly once. On August 4, 1923, St Kilda beat Richmond 60-25, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 60-25 in league history.
That makes 60-25 the 3836th most common final score out of 6,607 that have ever occurred in AFL. One point away, 61-25 has happened 2 times and 60-26 has happened never.