Has an AFL game ever ended 62-21?
Exactly once. On June 4, 1898, Sydney beat St Kilda 62-21, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 62-21 in league history.
That makes 62-21 the 3836th most common final score out of 6,607 that have ever occurred in AFL. One point away, 63-21 has happened never and 62-22 has happened 2 times.