Has an AFL game ever ended 64-3?
Exactly once. On July 10, 1897, Sydney beat St Kilda 64-3, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 64-3 in league history.
That makes 64-3 the 3836th most common final score out of 6,607 that have ever occurred in AFL. One point away, 65-3 has happened never and 64-4 has happened never.