Has an AFL game ever ended 64-45?
Yes. AFL has seen a final score of 64-45 2 times. It first happened on May 7, 1949, when Carlton beat Essendon, and most recently on July 23, 2017, when Richmond beat GWS.
That makes 64-45 the 2421st most common final score out of 6,607 that have ever occurred in AFL. One point away, 65-45 has happened 5 times and 64-46 has happened 4 times. At one point the score disappeared for 68 years, between 1949 and 2017.