Has an AFL game ever ended 64-49?
Exactly once. On August 22, 1953, Melbourne beat Fitzroy 64-49, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 64-49 in league history.
That makes 64-49 the 3836th most common final score out of 6,607 that have ever occurred in AFL. One point away, 65-49 has happened 4 times and 64-50 has happened never.