Has an AFL game ever ended 66-16?
Exactly once. On July 17, 1897, Geelong beat Carlton 66-16, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 66-16 in league history.
That makes 66-16 the 3836th most common final score out of 6,607 that have ever occurred in AFL. One point away, 67-16 has happened never and 66-17 has happened never.