Has an AFL game ever ended 66-25?
Yes. AFL has seen a final score of 66-25 3 times. It first happened on May 30, 1908, when St Kilda beat Melbourne, and most recently on August 13, 2020, when Sydney beat GWS.
That makes 66-25 the 1599th most common final score out of 6,649 that have ever occurred in AFL. One point away, 67-25 has happened never and 66-26 has happened 1 times. At one point the score disappeared for 102 years, between 1918 and 2020.