Has an AFL game ever ended 74-53?
Yes. AFL has seen a final score of 74-53 3 times. It first happened on June 25, 1921, when Sydney beat Geelong, and most recently on May 29, 2016, when Footscray beat Collingwood.
That makes 74-53 the 1534th most common final score out of 6,607 that have ever occurred in AFL. One point away, 75-53 has happened 5 times and 74-54 has happened 6 times. At one point the score disappeared for 52 years, between 1964 and 2016.