Has an AFL game ever ended 75-25?
Exactly once. On August 14, 2004, Geelong beat Fremantle 75-25, and no AFL game before or since has ended that way. When it happened it was a scorigami, the first 75-25 in league history.
That makes 75-25 the 3836th most common final score out of 6,607 that have ever occurred in AFL. One point away, 76-25 has happened never and 75-26 has happened 1 times.