Has an AFL game ever ended 78-35?
Yes. AFL has seen a final score of 78-35 2 times. It first happened on May 18, 1912, when Geelong beat Melbourne, and most recently on August 29, 1914, when Sydney beat Melbourne.
That makes 78-35 the 2421st most common final score out of 6,607 that have ever occurred in AFL. One point away, 79-35 has happened 3 times and 78-36 has happened 2 times.