Has an AFL game ever ended 80-65?
Yes. AFL has seen a final score of 80-65 6 times. It first happened on July 1, 1911, when Sydney beat Carlton, and most recently on April 5, 2009, when Footscray beat North Melbourne.
That makes 80-65 the 342nd most common final score out of 6,607 that have ever occurred in AFL. One point away, 81-65 has happened 8 times and 80-66 has happened 3 times. At one point the score disappeared for 45 years, between 1942 and 1987.