Has an NCAA Baseball game ever ended 25-1?
It has. 25-1 has been a NCAA Baseball final 40 times in 291,897 games. The first was Maryland beat Coppin State on May 2, 1989; the latest was Samford beat VMI on May 7, 2021.
That makes 25-1 the 236th most common final score out of 531 that have ever occurred in NCAA Baseball. One point away, 26-1 has happened 23 times and 25-2 has happened 30 times. Nearly all of its occurrences fall between 1980 and 2009.