Has an MLB game ever ended 24-1?

Exactly once. On September 9, 1882, Chicago White Stockings beat Troy Trojans 24-1, and no MLB game before or since has ended that way. When it happened it was a scorigami, the first 24-1 in league history.

Where 24-1 sits among nearby MLB scores. Deeper blue means a score has happened more often; the outlined cell is the new one.

That makes 24-1 the 278th most common final score out of 330 that have ever occurred in MLB. One point away, 25-1 has happened 2 times and 24-2 has happened 5 times.

Every 24-1 in MLB history

Date	Result	Season
1882-09-09	Chicago White Stockings over Troy Trojans	1882

Open the MLB grid at 24-1