Has an MLB game ever ended 25-13?

Exactly once. On June 9, 1901, New York Giants beat Cincinnati Reds 25-13, and no MLB game before or since has ended that way. When it happened it was a scorigami, the first 25-13 in league history.

Where 25-13 sits among nearby MLB scores. Deeper blue means a score has happened more often; the outlined cell is the new one.

That makes 25-13 the 278th most common final score out of 330 that have ever occurred in MLB. One point away, 26-13 has happened never and 25-14 has happened never.

Every 25-13 in MLB history

Date	Result	Season
1901-06-09	New York Giants over Cincinnati Reds	1901

Open the MLB grid at 25-13