Has an NPB (Japan) game ever ended 16-2?
Yes. NPB (Japan) has seen a final score of 16-2 21 times. It first happened on October 28, 1950, when Chunichi Dragons beat Kokutetsu Swallows, and most recently on June 19, 2025, when Fukuoka Softbank Hawks beat Hiroshima Toyo Carp.
That makes 16-2 the 116th most common final score out of 223 that have ever occurred in NPB (Japan). One point away, 17-2 has happened 13 times and 16-3 has happened 20 times.