Has an NCAA Women's Basketball game ever ended 53-40?
It has. 53-40 has been a NCAA Women's Basketball final 45 times in 129,040 games. The first was Notre Dame Fighting Irish beat Virginia Tech Hokies on January 10, 2004; the latest was Alcorn State Lady Braves beat Arkansas-Pine Bluff Golden Lions on February 8, 2025.
That makes 53-40 the 840th most common final score out of 3,854 that have ever occurred in NCAA Women's Basketball. One point away, 54-40 has happened 34 times and 53-41 has happened 40 times. Nearly all of its occurrences fall between 2010 and 2039.