Has a College Football game ever ended 109-0?

Exactly once. On October 7, 1905, Colorado beat Regis (CO) 109-0, and no College Football game before or since has ended that way. When it happened it was a scorigami, the first 109-0 in league history.

Where 109-0 sits among nearby College Football scores. Deeper blue means a score has happened more often; the outlined cell is the new one.

That makes 109-0 the 1820th most common final score out of 2,216 that have ever occurred in College Football. One point away, 110-0 has happened 4 times and 109-1 has happened never.

Every 109-0 in College Football history

Date	Result	Season
1905-10-07	Colorado over Regis (CO)	1905

Open the College Football grid at 109-0