Has a College Football game ever ended 146-3?
Exactly once. On November 17, 1916, Rice beat SMU 146-3, and no College Football game before or since has ended that way. When it happened it was a scorigami, the first 146-3 in league history.
That makes 146-3 the 1819th most common final score out of 2,215 that have ever occurred in College Football. One point away, 147-3 has happened never and 146-4 has happened never.