Has a College Football game ever ended 21-21?
It has. 21-21 has been a College Football final 75 times in 84,334 games. The first was Penn State and Harvard drew on October 22, 1921; the latest was USC and Washington drew on October 28, 1995.
That makes 21-21 the 291st most common final score out of 2,215 that have ever occurred in College Football. One point away, 22-21 has happened 76 times and 21-22 has happened never.