Has a College Football game ever ended 44-2?
Exactly once. On November 1, 1913, Lafayette beat Ursinus 44-2, and no College Football game before or since has ended that way. When it happened it was a scorigami, the first 44-2 in league history.
That makes 44-2 the 1819th most common final score out of 2,215 that have ever occurred in College Football. One point away, 45-2 has happened 4 times and 44-3 has happened 26 times.