Has a College Football game ever ended 52-50?
Exactly once. On November 24, 2007, Tennessee beat Kentucky 52-50, and no College Football game before or since has ended that way. When it happened it was a scorigami, the first 52-50 in league history.
That makes 52-50 the 1820th most common final score out of 2,216 that have ever occurred in College Football. One point away, 53-50 has happened 1 times and 52-51 has happened 7 times.