Has a College Football game ever ended 59-49?
Yes. College Football has seen a final score of 59-49 2 times. It first happened on October 26, 2013, when SMU beat Temple, and most recently on November 11, 2018, when Temple beat Houston.
That makes 59-49 the 1611th most common final score out of 2,216 that have ever occurred in College Football. One point away, 60-49 has happened 1 times and 59-50 has happened 1 times.